The court seized the hotel. Can the hotel remain open?

Of course, the hotel can continue to operate.

Article 155 of the Interpretation of the Supreme People's Court on the Application of the Civil Procedure Law of People's Republic of China (PRC), if the continued use of the property designated by the people's court to be kept by the preserved person has no significant impact on the value of the property, the preserved person may be allowed to continue to use it; The people's courts and other custodians shall not use the property kept by the people's courts or entrusted by others or applied for custody.