At around 6:00 on April 14, 2013, a fire broke out at Yijing City Garden Hotel on Qianjin East Road, Fancheng District, our city. The fire caused 61 casualties, of which 14 have been confirmed.

A. Cover your mouth and nose with a wet towel to prevent inhaling toxic gases or smoke, so the option is correct.

B. Smoke and toxic gases can rise with the hot air flow. Lying on the ground and crawling forward to escape can prevent inhalation of smoke, so the optional measure is correct.

C. When the escape route is cut off, close the doors and windows tightly, block the door gaps with wet towels or wet cloths, or soak the quilts with water to cover the doors and windows to prevent the penetration of fireworks and wait for help. Therefore, the optional measures are correct.

D. Jumping from a high-rise building can cause serious injury or even death, so the option option is wrong.

So choose D.