Is online hotel reservation reliable? Which website do you usually go to make reservations?

Reliable. There is generally no need to pay a deposit. There is nothing wrong with big websites. Don't worry about being cheated.

Some small websites, at first glance, know that there is a problem. Don't be too greedy and cheap.

I used many websites to make reservations. At present, my personal choice is Travellink 198, which is quite cheap and affordable. I suggest you have a look.