Can the hotel clean the room?

Yes, ask the front desk to ask the housekeeper to clean it.

You can directly tell the hotel front desk that you need to clean the room, and then make an appointment to clean it. Normally, someone will come to clean it every other day. If you don't want people to come in and clean, just put the washless side of the sign on the doorknob outside the door. The waiter won't come in to clean.