What are the big cows in analytical chemistry? What is the future development direction?

Zhihu users analyze chemical brick movers.

Because my undergraduate course is electrical analysis, and Shuobo is electrochemical luminescence, so the answer here is more photoelectric. Mass spectrometry and chromatography direction, can only do our best.

As far as my own direction is concerned, the best in the world is undoubtedly Allen J Budd. This man seems to be the founder of electrochemical scanning microscope. Then, related to him, his disciple Hou Bo is now doing a lot of electrochemiluminescence and electrochemical scanning microscopy. For example, Ding Zhifeng in Canada, Paul Francis in Australia, Mark Richter and Miao Wu Jian in the United States. Then the related imaging was also done by Tao Nongjian of Arizona State University. In addition, Joeph Wang of the University of San Diego has actually done a good job in electrochemistry. He himself is the editor-in-chief of Electrolytic Analysis. However, in recent years, it seems that I have switched to nanomaterials. I haven't read much about the recent literature, and the details are not clear.

Another teacher who pays more attention to articles should be Lin Wenbin of the University of Chicago. Teacher Lin Wenbin has done a series of work on the synthesis of luminescent MOFs and its application in biosensing, cell sensing and cell imaging. I really want to meet a real person one day!

Few people do electrochemical scanning microscope in China, but there are many electrochemical luminescence. Moreover, electrochemiluminescence and fluorescence have many intersections, which are mentioned here. Mr. Changchun Institute and Mr. Dong started from electrochemistry, and have made brilliant achievements in electrochemiluminescence and fluorescence in recent years. Mr. Wang mainly makes new fluorescent materials and electrochemical luminescent materials, such as copper clusters, gold clusters and syndicated clusters. Teacher Dong seems to have a soft spot for carbon dots, and there are many works related to carbon dots. Then many of their disciples did well. In recent years, researcher Sun published six JACS on 14 (Teacher Sun has joined Sichuan University full-time). ECL of Changchun Huaying College Another awesome person should be Teacher Xu Guobao. In his early years, Mr. Xu Guobao did a series of work from new co-reactive reagents to new luminescent materials and materials for promoting luminescence. The other has started from electrochemistry, and later turned to be a luminous academician. Mr Chen Hongyuan of Nantah should say that he is good at teaching apprentices. Several apprentices basically do electrochemiluminescence, fluorescence and electrochemistry. Famous disciples include Professor Zhang Shusheng from Linyi University (Yangtze River) and Professor Xu Jingjuan from Nanjing University (Yangtze River) (xu teacher seems to pay more attention to the energy transfer of electrochemiluminescence, and then he also has some work in photoelectrochemistry). In addition, there seems to be some ecl imaging work, mainly combining microfluidic to do ecl visual inspection, which is very creative! Professor (Jie Qing) (Mr. Zhu should still have done the most electrochemical work. His doctor Zheng Tingting has made a series of electrochemical cell sensors. In addition, I also saw some innovative work such as impedance imaging. In recent years, there has also been some work by ECL and Page. In addition to the first time, Mr. Zhu has also done a series of microbial fuel cells and cancer cell treatment in recent years. Yang's work is excellent. Professor Ju Xianxian (Changjiang) (Mr. Ju's work is mixed, including electrochemistry, ECL, PEC, fluorescence, Raman, mass spectrometry and cell imaging. However, the basic center is still based on various signal amplification methods), Li Genxi (Xie Qing) (Teacher Li seems to have done more work on peptide fragments in the past two years, basically doing electrochemistry) (These teachers basically do life analysis by photoelectric means. Such as microRNA and target DNA detection, cell detection, cell imaging, etc. ). Two academicians who have been doing electrical analysis, Mr. Yu Ruqin and Mr. Yao Shouzhuo of Hunan University, are also the older generation. Yu Xiansheng is mainly engaged in the research of chemometrics and chemical sensing. Among the disciples, Professor Yuan Ruo from Southwest University, Professor Wu Hailong from Hunan University, Professor Jiang Jianhui from Sichuan University and Professor Xiao Dan are all well-known experts in this field. Professor Wang Kemin from Hunan University and Professor Yang Ronghua from Changsha University of Science and Technology also did very well! Speaking of sensors, the international bull must be itamar willner of Israel. Mainly study various chemical or biological sensors. I also forgot a great electrochemist, Professor Pang of Wuhan University, who started with electrochemistry. In recent years, it has mainly turned to the synthesis of quantum dots and virus labeling. Scientific research is very difficult, but the results are remarkable and powerful. In addition, Mr. Chen of Fuzhou University is also an old-timer who has made great achievements in optoelectronics and enjoys a worldwide reputation. However, it seems that I haven't taken students personally in recent years. The details are not clear. In the tide of teachers in Fuzhou University, individuals prefer to chase after the papers of teacher Chi Yuwu. Mr. Chi should be a creative and thoughtful teacher. The combination of various instruments and the synthesis of various new luminescent materials are excellent. It seems that the earliest carbon point graphene quantum dots were made by Dr. Dong Yongqiang. Later, there were some C3N4 jobs in Dong Yongqiang. But according to the number of years, I should graduate, right After being a doctoral student with Mr. Chi? Besides, Miss Yang did a great job! Amway's visit to Tang Ping, a teacher at Fuda University, is definitely a promising young teacher. Moreover, his struggle experience is legendary, and those who are interested can learn about it, which is very inspirational! ! ! Mr. Zhang, the originator of domestic chemiluminescence, also led the trend of domestic chemiluminescence research. Mr. and Mr. Qi of Shaanxi Normal University also inherited Mr. Zhang's mantle and did a good job.

Then, in fact, many research groups that do inorganic, especially rare earth luminescence, now rely on cell imaging to analyze. For example, Academician Yao Jiannian from Beijing Institute of Chemistry and Academician Zhao Dongyuan from Fudan University. In the past, their work seemed to focus on the synthesis of fluorescent materials. There is also a lot of cell imaging work now.

From a small point of view, there are only a few awesome people in some directions in China. For example, Professor Tang Bo of Shandong Normal University who does two-photon fluorescence, and Professor Ma Huimin of the Institute of Chemistry (both Xie Qing). Mr. Fan Chunhai, DNA configurator, from Shanghai Institute of Applied Physics. Pretreatment, Professor Li from Sun Yat-sen University. There are also teachers Zhang Xinrong from Tsinghua University, Professor Zhang Sichun from Peking University and Professor Liu Huwei who do mass spectrometry. Mr. Hou, a teacher of atomic fluorescence in Sichuan University (thanks for correcting me in the comments). Professor Mao Lanqun, who has done bioelectricity analysis in Beijing Institute of Chemistry, is rare in China. Another person who has made some achievements in bioelectricity analysis may be Tian Yang, a teacher from East China Normal University. There are few people who do biology in the world, such as Andrew Ewing of Sweden. Even fewer people make musical instruments. Well done, Huangyan Yi (who just evaluated Jie Qing this year), Tsinghua University and Changchun Huaying College are all in the minority. For example, at the National Nanometer Center, Mr. Jiang Xingyu. In addition, some directions have high requirements for equipment and great difficulties in scientific research, and there are few outstanding achievements in China, so I won't introduce them here (such as spr, spri, Raman spectroscopy, etc. ).

If you are a star of tomorrow, look at the 10,000 people in China, and Qian Qing will know. For example, Kaho of Huazhong University of Science and Technology, Yolanda of Wuhan University, Chu Xia of Hunan University, Wang Wei of Nanjing University, Wu Peng of Sichuan University and so on.

As for the development direction of analytical chemistry? This shovel officer is still studying for a doctorate, and he dare not write such a big paper casually. I can only say a little about what I saw. At the two extremes, it is still a minimalist route, so that ordinary people can do tests at home. For example, commercial small-scale tests such as ph test paper, early pregnancy and blood glucose meter. Either go high-tech, units without large instruments and equipment can't do it, and pursue high sensitivity! For example, more sensitive mass spectrometry is needed, and some blood tests, urine tests and pesticide residues with extremely low detection limits are needed.

In addition, as far as scientific research is concerned, many papers that want to do better now seem to be transforming their own instruments and making data that others can't do. Some instruments are even customized! It is very outdated to rely entirely on instrument manufacturers. For example, electrochemical workstation is combined with ultraviolet spectrophotometer, spr and even Raman spectrometer.