Excuse me, what's in my hand? I had it when I was a kid. The doctor said it was telangiectasia. The picture turned purple because of the cold weather. Usually,

Congenital telangiectasia

1. Hereditary hemorrhagic telangiectasia: autosomal dominant inheritance.

2. Ataxia telangiectasia: autosomal recessive inheritance.

3.Bloom syndrome: autosomal recessive inheritance

4.Goltz syndrome: autosomal recessive inheritance.

5. Congenital telangiectatic marble dermatosis

6. Spider plague: It can be congenital or acquired.

Senile telangiectasia

It is caused by physiological skin atrophy, relaxation and poor elasticity.

People with other diseases

1. Spider fatigue is very common. Pregnancy caused by liver disease may be related to estrogen.

2. telangiectatic lupus erythematosus is a rare type of lupus erythematosus, which may be related to vascular dysfunction caused by photosensitive and autoimmune mechanisms.

3. Persistent macular telangiectasia is a special type of pigmented measles.

4. Sjogren's syndrome may be related to high gamma globulin.

5. The etiology of telangiectatic annular purple disease is unknown, which belongs to periductal lymphangitis.

Secondary telangiectasia

1. Congenital heredity ① Congenital skin heterochromia; ② Congenital dyskeratosis; ③ xeroderma pigmentosum; It is autosomal recessive inheritance.

2. Vascular diseases ① hemangioma; ② Angiofibroma; ③ Varicose veins of angioatrophic skin heterochromia; ⑤ Nodular polyarteritis; (3) Spasm of extremity artery

3. Physics ① Chronic radiation dermatitis; ② solar dermatitis; (3) Steel workers cook for a long time.

4. Endocrine ① Diabetic lipid-like progressive necrosis; ② rosacea; ③ Pregnant women; ④ Abnormal estrogen in liver disease.

5. Others ① Systemic mastocytosis; ② Canceration; ③ Eosinophilic granuloma; ④ Breast cancer; ⑤ Epilepsy papules

6. Immunity ① Lupus erythematosus; ② Scleroderma; ③ Dermatomyositis

Second diagnosis

According to the analysis of the etiology and pathogenesis of telangiectasia, children and adolescents are mostly congenital, and their characteristics are often complicated with other tissue dysplasia, and most of them have a family history. Most of them are adults without family history, and those with unknown secondary causes are more common: comprehensive analysis of vascular diseases, autoimmune diseases and somatic endocrine factors combined with the characteristics and morphology of clinical telangiectasia can make a correct diagnosis.

Differential diagnosis of congenital telangiectasia

1. Hereditary hemorrhagic telangiectasia is autosomal dominant, and there is no gender difference, which is more common after puberty.

Skin lesions mainly occur on the back of hand, face, scrotum plexus and integrated rash patches. Spider-like star-shaped lesions can be seen around, and can also be seen in the parts such as lips, tongue, nose, membrane cheek or membrane gum that cause hemorrhagic lesions with bleeding.

2.* * * Ataxia telangiectasia, also known as syndrome, is autosomal recessive inheritance. 2-3 years old, characterized by cerebellar ataxia. The telangiectasia of eyes and skin starts from bulbar conjunctiva and then spreads to J fossa of eyelid, cheek, auricle, neck and elbow fossa, accompanied by nystagmus.

There are often coffee spots, white hair and premature aging.

3. The syndrome is autosomal recessive inheritance.

In childhood, Wei Ru's facial telangiectasia, allergic to light, and water scars often appear on the exposed part, which is serious in summer. In addition, there are ichthyosis, acanthosis nigricans, irregular teeth, cryptorchidism with big ears, coffee spots and other developmental abnormalities.

4.Goltz syndrome is an X-linked dominant inheritance, and male patients are fatal. All the literature reports are female, characterized by extensive dysplasia of ectodermal and mesodermal leaves, mainly manifested as linear telangiectasia of buttocks, armpits and thighs, well-defined cribriform skin atrophy spots, reddish-brown papilloma of oral perianal area and vulva, and fingerless scoliosis.

5. Congenital telangiectasia of marble skin, characterized by extensive reticular macula with spider nevus and angiokeratoma at birth, which can subside.

6. Spider fatigue can be congenital or acquired. The former is more common in children, while the latter is more common in liver diseases and pregnant women. Systemic primary telangiectasia is more common in children or adolescents. It starts from the calf and extends to the thigh, abdomen, buttocks and upper arm. Systemic sexually transmitted diseases will spread throughout the body. Skin atrophy, thinning, relaxation and poor elasticity are easy to cause telangiectasia, mostly in the face and lower limbs.

Third secondary telangiectasia

1. Long-term use of corticosteroids can cause telangiectasia, and external use can also occur locally. "

2. telangiectatic lupus erythematosus: a rare type of lupus erythematosus, which may be related to the changes of blood vessels caused by sunlight sensitivity and autoimmune mechanism.

3. Persistent macular telangiectasia: it is a special type of measles such as pigmentation.

4. Sjogren's syndrome: It may be related to hyperglobulinemia.

5. Cyclic violet of telangiectasia: Unexplained reasons are more common in adults. Perivascular bronchiolitis of lymphocytes in both legs is caused by yellow-red round punctate needle tips, with large ecchymosis and vasodilation, which can last for several years.

4 prevent and avoid all factors that can promote and aggravate bleeding, and avoid using drugs that can increase blood volume, raise blood pressure, dilate blood vessels and promote bleeding.

Daily precautions: avoid alcohol and tobacco stimulation, eat reasonably and avoid spicy food. Prevent and treat constipation, and supplement vitamins and trace elements. Keep enough sleep and pay attention to the combination of work and rest.

Hope to adopt!