Why coronary heart disease is a climate disease?

In cold weather or winter and spring, the incidence of angina pectoris and myocardial infarction will increase. It is because cold stimulation, especially running against the wind, is easy to excite sympathetic nerves, accelerate heart rate, raise blood pressure, contract systemic blood vessels, increase peripheral resistance and increase myocardial oxygen consumption. At the same time, it can also induce coronary artery spasm, make the lumen continuously occluded, or squeeze plaque to cause intimal injury, platelet aggregation, thrombosis to cause acute occlusion of the lumen, and also lead to acute myocardial infarction.