Is it safe to book a hotel on Taobao?

It's not safe. The hotel will only cooperate with the portal website, and will not cooperate with online stores like retail investors on Taobao. The reason why they can book a room at a low price is to use an account with a credit card, not a formal channel. If your channel hotel tells the front desk staff that your reservation was bought in Taobao, then you should be prepared not to check in. If the online store finds that you can't check in because of "disclosure", it won't give you a refund.