Grassley Shinjuku Hotel Tokyo

Go directly to JR Osaka Station, take the "JR Kyoto Line Express (Sanyuan Line)" and get off at Shin Osaka, then transfer to Shinkansen No.390 (N700 Series) (Tokyo Line), and get off at Shinagawa Station and transfer to JR Yamanote Line. It takes about three and a half hours, and the Shinkansen is the fastest. From New Osaka to Shinagawa, the price is about 14650 yen, just change trains twice. The trains in Japan are very punctual. See if you are sure when you want to take the train. You can ask me the specific time, such as the number of trains on the Shinkansen.