Anticoagulation principle of sodium citrate

Sodium citrate (sodium citrate) can form soluble complexes with calcium ions, which can be used as anticoagulant and blood transfusion agent, and for the preservation and processing of blood products.

Sodium citrate is used as flavoring agent and stabilizer in food and beverage industry. Used as anticoagulant, expectorant and diuretic in pharmaceutical industry; In the detergent industry, it can replace sodium tripolyphosphate as an auxiliary agent of non-toxic detergent; Chemically, it is an excellent chelating agent/complexing agent for industrial application of sodium citrate. It is also used in brewing, injection, photography and electroplating.

Sodium citrate can be used as a preservative to preserve drugs such as syrup. Like potassium salt, sodium citrate is used as a diuretic and expectorant to correct the acidity of blood, body fluids and urine. Sodium citrate combined with other reagents can be used to extract and purify animal liver RNA.

Extended Data Sodium citrate has the characteristics of good water solubility, excellent chelating ability to metal ions such as Ca2+ and Mg2+ in water, biodegradability, strong dispersibility and anti-redeposition, so it is gradually becoming a substitute for sodium tripolyphosphate, which is used to produce phosphorus-free washing powder, especially phosphorus-free liquid detergent. Adding a certain amount of sodium citrate to detergent can obviously increase the decontamination ability of detergent.

The extensive application of sodium tripolyphosphate as builder in detergent is an important discovery in synthetic detergent industry. However, phosphate is discharged into rivers and lakes with washing sewage, which causes eutrophication of water quality, promotes rapid propagation of aquatic algae, and endangers the survival of aquatic animals due to lack of oxygen in water, which has become a major problem in environmental protection.

The liquid detergent containing sodium citrate has excellent washing performance, so many special detergents have been developed at home and abroad. Liquid detergents containing sodium citrate also have other excellent properties, such as some special detergents containing sodium citrate are non-corrosive to some metal utensils, so they can be specially used to clean expensive precision instruments.

After cleaning the appliance with some special detergents containing sodium citrate, the metal surface is as bright as new, and the cleaned waste liquid can be recycled after treatment, which reduces the washing cost. It is reported that in order to solve the problem of pesticide residues in vegetables and fruits, relevant experts have developed a special cleaning agent for pesticide residues in vegetables and fruits containing sodium citrate.

Sodium citrate is widely used in electroplating industry because of its good complexing performance. In the construction industry, sodium citrate can be added to concrete as a retarder to improve the tensile, compressive and frost resistance of cement products; In environmental protection, sodium citrate can be used to remove sulfide from industrial tail gas. In the ceramic industry, sodium citrate can be used as a grinding aid. In addition, sodium citrate also has new uses in wine making and photography, thus further broadening the application field of sodium citrate.

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