What is congenital bronchiectasis?

Congenital is less common. It is due to congenital bronchial dysplasia. There are congenital defects or genetic diseases that prevent the peripheral lungs from further development, resulting in the development of bronchiectasis, such as bronchial chondrodysplasia ( Williams-Camplen syndrome). In some patients, bronchiectasis occurs after birth, but there are also congenital abnormalities, such as Kartagener syndrome. In addition to bronchiectasis, patients may also be accompanied by visceral ectopia and pancreatic cystic fibrosis. It actually belongs to ciliary akinetic syndrome. A subtype of immotile cilia syndrome. Bronchiectasis is also seen in Young syndrome, which is characterized by obstructive azoospermia, chronic sinusitis, recurrent lung infections, and bronchiectasis. Some patients with bronchiectasis show immunoglobulin deficiencies.

IgG deficiency is prone to repeated bacterial infections, among which IgG2 and IgG4 deficiencies are more important.