My 4-year-old child suffers from severe eczema and itchiness at night every winter. I don’t know what causes it.

The four major causes of eczema in children: endogenous, exogenous, skin barrier function and Staphylococcus aureus infection:

1. Exogenous triggering factors of eczema: food allergy : The main food allergens for children with eczema allergies less than three years old are eggs>milk>soybeans>wheat>peanuts.

2. Endogenous triggering factors of eczema: Intestinal mucosal barrier dysfunction: Food allergies first occur in the intestine. Because children’s eczema occurs in the skin, it is difficult to connect it with intestinal function. , but the intestinal mucosal barrier function is the first place to induce food allergies in infants and young children, and because this cause is not taken seriously by medical institutions and parents, the treatment of children's eczema is more limited to the treatment of skin rashes. Since the causative factors of children's eczema cannot be fully grasped and comprehensively regulated, this is the main reason for the repeated recurrence of eczema in infants and young children that cannot be cured for a long time.

3. Causes of eczema skin and mucosal damage: Damage to the skin and mucosal barrier (HDM_protease): Increased secretion of cytokines by keratinocytes. The human skin barrier is divided into 4 epidermal components:

The first layer is the microbial barrier (also called the bacterial barrier). If you put the human skin under a microscope, you will see that they are all bacteria. Therefore, for eczema In children, it is not recommended to wash the skin excessively. Many of the new modern lifestyles are destroying the human body's microbial barrier.

The second layer is the physical barrier

The third layer is the chemical barrier

The fourth layer It is an immune barrier

4. Staphylococcus aureus infection: This is basically the most ignored factor in the current treatment of infantile eczema. This is also the main reason why infantile eczema does not heal during the development and later stages. reason. It is also inseparable from eczema skin and mucosal damage, because children with eczema have long-term skin itching - scratching - itching - scratching again to form a vicious cycle, which leads to Staphylococcus aureus infection of the skin and mucous membranes and stimulates the secretion of skin keratinocytes. The main reason for the increase in factors is that in the later stages of baby's eczema, the skin will undergo changes such as lichen-like thickening and blackening.

The impact of eczema on the production quality of young children:

Due to skin eczema, which has long troubled the growth and development of young children and is a stubborn rash, it can appear in any part of the child's body, including eczema on the head and face, and Stubborn eczema on the limbs has become the most typical type of eczema in school-age children aged 2-6. The biggest disease characteristic of eczema is itching, which can be called extreme itching in medicine. Children's eczema seriously affects the child's sleep and the life he is about to enter. campus life. As the child grows up, the long-term trouble of eczema causes the child and the entire family to fall into pain and depression, and can also lead to the child's loneliness.

The proportion of childhood eczema in each age group:

(<6 months) Early infant eczema: Eczema appears about 30 days after birth, and the clinical incidence rate is 53% , mainly due to milk protein allergy;

(6-12 months) mid-term infant eczema: clinical incidence rate is 23%, the onset is still mainly food allergy, but there may be many allergens This is the stage when babies start to add complementary foods, and it is also a period when allergies are very likely to occur;

(>12 months) Late childhood eczema: the clinical incidence rate is 25%, and it is easy to develop into ectopic Sexual dermatitis, the course of the disease is easily extended into adolescence.

New progress in the basic treatment of children with eczema (anti-allergic probiotics + skin moisturizing emollient + skin antibacterial) is the basic therapy to reduce the use of hormones in children with eczema.

Aiming at the causes of eczema in children: increased allergic IgE - skin damage and infection - skin barrier dysfunction, these three causes are closely related to the onset and development of eczema, summarized by experts on anti-allergic probiotics Three necessary conditions for treating eczema:

1. Supplementing anti-allergic probiotics (not less than 3 months) can reduce serum IgE allergic antibodies, build the baby's intestinal barrier function, and adjust allergic constitution;

2. Very necessary anti-inflammatory treatment: use Baiduobang ointment externally on damaged skin to resist infection;

Reduce bathing, as eczema will aggravate when exposed to moisture. Furthermore, babies with eczema are born with congenital If the skin barrier function is not perfect and the skin's sebum layer is not synthesized, bathing should be reduced and skin emollients should be used to protect the skin.

3. Extensive application of skin moisturizers to care for the skin: to combat dryness and restore the barrier function of the skin, emollient containing medicinal urea is better, and 10% urea cream is beneficial to enhancing the patient's skin barrier function. .

1. Early diagnosis and avoid contact with allergens

2. Anti-allergic probiotic intestinal immunity for children with eczema: In the intestinal immune system, there is a kind of "immune tolerance" The mechanism inhibits the immune system and secretes immunoglobulin E (IgE) or G (IgG) that can cause allergic reactions in response to food ingredients. For people with allergies, there is a problem with the "immune tolerance" mechanism. Therefore, when eating a specific food, the intestinal immune system will secrete too much immunoglobulin E (IgE) to attack the food ingredients, resulting in allergic reactions. Allergy.

Among the four major allergic diseases, the onset of atopic dermatitis in children and baby eczema is closely related to the child's intestinal "immune tolerance" dysfunction. Children with allergies will develop allergies after birth. Due to problems with the "immune tolerance" of the baby's intestinal function, infant eczema, physiological diarrhea, etc. will occur to varying degrees within one year of age. In addition, the current overuse of antibiotics in children's medical care will directly affect the "immune tolerance". If there is a problem with the balance of the "receptor" mechanism and the "immune tolerance" mechanism, it will first lead to excessive secretion of immunoglobulin E (IgE), prompting the immune response to move towards the Th2 pathway, and young children are prone to allergic symptoms.

Due to the intuitive understanding of the cause-and-effect relationship between the symptoms of baby skin eczema and the "immune tolerance" disorder of excessive IgE secretion, the intestinal IgE immune function of children is easily ignored, which in turn makes children allergic. The reaction continues to aggravate and develop, and will generally follow the order of atopic dermatitis (eczema) - allergic asthma - allergic rhinitis. Although taking anti-allergic drugs or even glucocorticoids and other drugs can inhibit the release of inflammation in the body The substance can quickly relieve allergic symptoms, but it cannot regulate the excessive secretion of IgE, so it can only relieve symptoms when they occur but cannot prevent the occurrence of allergic symptoms, nor can it improve allergic constitution through the "immune tolerance" mechanism.

Children with allergies lack good bacteria in their intestines

There are many types of allergens, such as: dust mites, bacteria, pollen, protein, milk, soybeans, wheat, mold, and meat. ..... etc., many medical studies have pointed out that allergy problems caused by "excessive secretion of immune tolerance IgE" are closely related to good and bad bacteria in the intestines. Studies have shown that children with allergies have fewer beneficial bacteria such as Lactobacillus in their intestines. Although tens of thousands of lactobacilli strains exist in nature, only a handful of lactic acid strains have anti-allergic properties. This kind of "immune" The strains that "tolerate IgE hypersecretion" and have special regulatory effects are Lactobacillus salivarius, Lactobacillus gasseri, Lactobacillus paracasei and Lactobacillus reuteri, which are known as anti-allergic probiotics. The effect of Lactobacillus salivarius is to reduce serum IgE antibodies, promote the secretion of interferon and improve the Th1 type immune response; while the effect of Lactobacillus gasseri is to reduce serum IgG, help to reduce the secretion of allergic reaction-related cytokine IL-5, which can effectively To enhance the body's immune system, anti-allergic probiotics have the ability to help adjust allergic constitution.