Traditional Culture Encyclopedia - Weather inquiry - In the weather of more than 20 degrees, will the external use of recombinant human epidermal growth factor not be put in the refrigerator overnight lead to failure? ,,

In the weather of more than 20 degrees, will the external use of recombinant human epidermal growth factor not be put in the refrigerator overnight lead to failure? ,,

Perhaps, if the room temperature does not exceed 20 degrees, you can continue to use it. If the temperature exceeds 20 degrees and the time is too long, the drug may denature, so it is not recommended to use it.

Growth factors are a kind of organic substances that are necessary to regulate the normal growth and metabolism of microorganisms, but cannot be synthesized by simple carbon and nitrogen sources. In addition to vitamins, growth factors in a broad sense include bases, purines, pyrimidines, biotin and nicotinic acid, and sometimes amino acids required by amino acid auxotrophs.

Growth factors in a narrow sense generally refer only to vitamins. A class of polypeptide substances that regulate cell growth and other cell functions by binding to specific high affinity cell membrane receptors. It exists in platelets, various adult and embryonic tissues and most cultured cells, and has certain specificity for different kinds of cells.

Usually, the growth of cultured cells needs the synergistic effect of various growth factors, and tumor cells have the characteristics of independent growth without relying on growth factors.

Characteristics of cytokines:

Cytokines refer to substances that can replace high molecular substances in culture medium serum and promote cell growth in tissue culture except normal components such as amino acids, vitamins, glucose and inorganic salts.

It is a cytokine with the activity of stimulating cell growth. A class of substances that regulate cell growth and other cell functions by binding to specific and high affinity cell membrane receptors.

It exists in platelets, various adult and embryonic tissues and most cultured cells, and has certain specificity for different kinds of cells. It is synonymous with development factor and proliferation factor, but because the direct purpose of tissue culture is cell proliferation, proliferation factor is more accurate.

Above content reference: Baidu Encyclopedia-Cytokines